They demonstrate stable epigenetic remodeling of the pax7 locus and uncover transcriptome wide differences that result from endogenous versus exogenous pax7 expression. 6 1 upon stimulation from exercise or following muscle injury satellite cells become activated and enter mitosis undergoing cellular division and giving rise to myogenic. In this way satellite cells have an important role in not only muscle development but in the maintenance of muscle through adulthood.
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